A 2015 study on rats, in which they ingested lion’s mane extract for 6 weeks, showed positive results, including lower blood sugar levels, reduced feelings of nerve pain, and improved antioxidant activity. One of the complications of diabetes is nerve damage resulting from prolonged periods of high blood sugar. In one study, blood sugar levels in rats with diabetes were lower after they received lion’s mane mushroom extract for 4 weeks. DiabetesĬontrolling blood sugar levels is key to managing diabetes. These findings are promising, but it is not currently possible to confirm that the same effects will apply in people. The results of an in vitro study indicate that lion’s mane extracts have therapeutic potential against human leukemia.Ī study using animal models found that these mushroom extracts may also fight liver, colon, and gastric cancer cells. The antioxidant properties of lion’s mane mushrooms may play a role in cancer prevention or treatment. Research on rats showed that the mushroom extracts might have a cholesterol-lowering effect. Lion’s mane extract may improve heart health, but the research to date has primarily used animal subjects. These scores decreased again once the participants stopped taking the extract. However, there is currently a lack of research on the effects of lion’s mane mushrooms in humans with Alzheimer’s disease.Īn older Japanese study on adults aged between 50 and 80 years with mild cognitive impairment found that daily consumption of mushroom extract for 16 weeks led to higher scores on cognitive function scales compared with a placebo group. Other researchers have concluded that the mushrooms may have the potential to treat or prevent diseases that cause a decline in cognitive health, such as Parkinson’s disease and Alzheimer’s disease. In one study, lion’s mane dietary supplements appeared to give mice better object recognition and recognition memory. It is possible that lion’s mane mushrooms might boost cognitive function, but the existing research is mainly on animals. The participants who ate the extract reported lower levels of irritation and anxiety than those in the placebo group. In a small Japanese study, women with a variety of health complaints, including menopausal symptoms and poor sleep quality, ate cookies containing lion’s mane extracts or placebo cookies for 4 weeks. The findings of a 2018 animal study support this, with the authors concluding that these mushroom extracts may contain agents that are useful for treating depressive disorders. The researchers suggest that this is due to the extract’s anti-inflammatory effects. In a 2015 study, mice that consumed lion’s mane mushroom extract displayed fewer depressive behaviors and had blood markers that indicated lower depression. Anxiety and depressionĮxtracts from lion’s mane mushrooms may be beneficial in the treatment of anxiety and depression. The results of another study on mice indicate that a protein in lion’s mane mushrooms encourages the growth of beneficial gut bacteria that strengthen immunity. Research on mice suggests that lion’s mane mushrooms may boost the activity of the intestinal immune system. Lion’s mane mushrooms may enhance the immune system, partly by reducing inflammation and preventing oxidation. Inflammation contributes to many medical conditions, including diabetes, heart disease, and autoimmune diseases.Ī 2012 study evaluating the medicinal potential of 14 types of mushroom found that lion’s mane had the fourth highest antioxidant activity, which researchers described as “moderate to high.” Immune function Share on Pinterest Lion’s mane mushrooms may offer a number of health benefits.Īntioxidants may fight both inflammation and oxidation in the body.
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